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Synthesis and biological evaluation of novel N(9)-heterobivalent β-carbolines as angiogenesis inhibitors
A series of novel N(9)-heterobivalent β-carbolines has been synthesized. All the novel compounds were tested for their anticancer activity against six tumour cell lines in vitro. Among these molecules, compounds 5b, and 5w exhibited strong cytotoxic activities with IC(50) value of lower than 20 μM....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327987/ https://www.ncbi.nlm.nih.gov/pubmed/30734606 http://dx.doi.org/10.1080/14756366.2018.1497619 |