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Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity

Acidity and hypoxia are crucial phenotypes of tumour microenvironment both contributing to the selection of malignant cells under a micro evolutionistic pressure. During the tumour progression, nanovesicles, called exosomes and the metalloenzyme carbonic anhydrase IX (CA IX) affect the tumour growth...

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Detalles Bibliográficos
Autores principales: Logozzi, Mariantonia, Capasso, Clemente, Di Raimo, Rossella, Del Prete, Sonia, Mizzoni, Davide, Falchi, Mario, Supuran, Claudiu T., Fais, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327996/
https://www.ncbi.nlm.nih.gov/pubmed/30734594
http://dx.doi.org/10.1080/14756366.2018.1538980