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Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity
Acidity and hypoxia are crucial phenotypes of tumour microenvironment both contributing to the selection of malignant cells under a micro evolutionistic pressure. During the tumour progression, nanovesicles, called exosomes and the metalloenzyme carbonic anhydrase IX (CA IX) affect the tumour growth...
Autores principales: | Logozzi, Mariantonia, Capasso, Clemente, Di Raimo, Rossella, Del Prete, Sonia, Mizzoni, Davide, Falchi, Mario, Supuran, Claudiu T., Fais, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327996/ https://www.ncbi.nlm.nih.gov/pubmed/30734594 http://dx.doi.org/10.1080/14756366.2018.1538980 |
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