Detection of CALR Mutations Using High Resolution Melting Curve Analysis (HRM-A); Application on a Large Cohort of Greek ET and MF Patients

BACKGROUND AND OBJECTIVES: Somatic mutations in the calreticulin gene (CALR) are detected in approximately 70% of patients with essential thrombocythemia (ET) and primary or secondary myelofibrosis (MF), lacking the JAK2 and MPL mutations. To determine the prevalence of CALR frameshift mutations in...

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Detalles Bibliográficos
Autores principales: Giannopoulos, Andreas, Rougkala, Niki, Loupis, Theodoros, Mantzourani, Marina, Viniou, Nora-Athina, Variami, Eleni, Vassilakopoulos, Theodoros P., Dryllis, George, Kotsianidis, Ioannis, Gougopoulou, Theodora, Politou, Marianna, Konstantopoulos, Kostas, Vassilopoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328041/
https://www.ncbi.nlm.nih.gov/pubmed/30671215
http://dx.doi.org/10.4084/MJHID.2019.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328041/
https://www.ncbi.nlm.nih.gov/pubmed/30671215
http://dx.doi.org/10.4084/MJHID.2019.009

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