Detection of CALR Mutations Using High Resolution Melting Curve Analysis (HRM-A); Application on a Large Cohort of Greek ET and MF Patients

BACKGROUND AND OBJECTIVES: Somatic mutations in the calreticulin gene (CALR) are detected in approximately 70% of patients with essential thrombocythemia (ET) and primary or secondary myelofibrosis (MF), lacking the JAK2 and MPL mutations. To determine the prevalence of CALR frameshift mutations in...

Descripción completa

Detalles Bibliográficos
Autores principales: Giannopoulos, Andreas, Rougkala, Niki, Loupis, Theodoros, Mantzourani, Marina, Viniou, Nora-Athina, Variami, Eleni, Vassilakopoulos, Theodoros P., Dryllis, George, Kotsianidis, Ioannis, Gougopoulou, Theodora, Politou, Marianna, Konstantopoulos, Kostas, Vassilopoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328041/
https://www.ncbi.nlm.nih.gov/pubmed/30671215
http://dx.doi.org/10.4084/MJHID.2019.009

Ejemplares similares

Ejemplares similares