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Enhancement of himastatin bioproduction via inactivation of atypical repressors in Streptomyces hygroscopicus

Three atypical regulatory genes, hmtABD have been discovered within the himastatin biosynthetic gene cluster (BGC) in Streptomyces hygroscopicus ATCC 53653 and the roles of their products have been identified. HmtA and HmtD do not show any structurally distinct features characteristic of regulatory...

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Detalles Bibliográficos
Autores principales: Xie, Yunchang, Li, Qinglian, Qin, Xiangjing, Ju, Jianhua, Ma, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328088/
https://www.ncbi.nlm.nih.gov/pubmed/30671346
http://dx.doi.org/10.1016/j.mec.2018.e00084