The Tuberin and Cyclin B1 complex functions as a novel G2/M sensor of serum conditions and Akt signaling

A great deal of ground breaking work has determined that the Tuberin and Hamartin Complex function as a negative regulator of protein synthesis and cell cycle progression through G1/S. This is largely attributed to the GTPase activity of Tuberin that indirectly inhibits the mammalian target of rapam...

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Detalles Bibliográficos
Autores principales: Fidalgo da Silva, Elizabeth, Botsford, Sabrina, Dare-Shih, Jessica, Hanna, Miranda A., Porter, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328093/
https://www.ncbi.nlm.nih.gov/pubmed/30629673
http://dx.doi.org/10.1371/journal.pone.0210612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328093/
https://www.ncbi.nlm.nih.gov/pubmed/30629673
http://dx.doi.org/10.1371/journal.pone.0210612

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