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The Tuberin and Cyclin B1 complex functions as a novel G2/M sensor of serum conditions and Akt signaling
A great deal of ground breaking work has determined that the Tuberin and Hamartin Complex function as a negative regulator of protein synthesis and cell cycle progression through G1/S. This is largely attributed to the GTPase activity of Tuberin that indirectly inhibits the mammalian target of rapam...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328093/ https://www.ncbi.nlm.nih.gov/pubmed/30629673 http://dx.doi.org/10.1371/journal.pone.0210612 |