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A plant-derived VLP influenza vaccine elicits a balanced immune response even in very old mice with co-morbidities
BACKGROUND: The elderly are at high risk from influenza, in part because immunity wanes with age and through the accumulation of comorbidities. A novel plant-derived virus-like-particle (VLP) vaccine bearing influenza hemagglutinin can induce a balanced humoral and cellular response in old mice (16–...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328122/ https://www.ncbi.nlm.nih.gov/pubmed/30629622 http://dx.doi.org/10.1371/journal.pone.0210009 |