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A plant-derived VLP influenza vaccine elicits a balanced immune response even in very old mice with co-morbidities

BACKGROUND: The elderly are at high risk from influenza, in part because immunity wanes with age and through the accumulation of comorbidities. A novel plant-derived virus-like-particle (VLP) vaccine bearing influenza hemagglutinin can induce a balanced humoral and cellular response in old mice (16–...

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Detalles Bibliográficos
Autores principales: Hodgins, Breanna, Pillet, Stephane, Landry, Nathalie, Ward, Brian James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328122/
https://www.ncbi.nlm.nih.gov/pubmed/30629622
http://dx.doi.org/10.1371/journal.pone.0210009