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Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes

Heat shock protein 90 (Hsp90) is a protein chaperone that is upregulated and released from pancreatic β cells under pro-inflammatory conditions. We hypothesized that serum Hsp90 may have utility as a biomarker of type 1 diabetes risk and exhibit elevations before the onset of clinically significant...

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Detalles Bibliográficos
Autores principales: Ocaña, Gail J., Sims, Emily K., Watkins, Renecia A., Ragg, Susanne, Mather, Kieren J., Oram, Richard A., Mirmira, Raghavendra G., DiMeglio, Linda A., Blum, Janice S., Evans-Molina, Carmella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328179/
https://www.ncbi.nlm.nih.gov/pubmed/30629603
http://dx.doi.org/10.1371/journal.pone.0208456