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Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes
Heat shock protein 90 (Hsp90) is a protein chaperone that is upregulated and released from pancreatic β cells under pro-inflammatory conditions. We hypothesized that serum Hsp90 may have utility as a biomarker of type 1 diabetes risk and exhibit elevations before the onset of clinically significant...
Autores principales: | Ocaña, Gail J., Sims, Emily K., Watkins, Renecia A., Ragg, Susanne, Mather, Kieren J., Oram, Richard A., Mirmira, Raghavendra G., DiMeglio, Linda A., Blum, Janice S., Evans-Molina, Carmella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328179/ https://www.ncbi.nlm.nih.gov/pubmed/30629603 http://dx.doi.org/10.1371/journal.pone.0208456 |
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