Exposure of Barrett’s and esophageal adenocarcinoma cells to Bile acids activates EGFR-STAT3 signaling axis via induction of APE1

The development of Barret’s esophagus (BE) and its progression to esophageal adenocarcinoma (EAC) is highly linked to exposure to acidic bile salts due to chronic gastroesophageal reflux disease (GERD). In this study, we investigated the role of Apurinic/apyrimidinic endonuclease 1 /redox effector f...

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Detalles Bibliográficos
Autores principales: Bhat, Ajaz A., Lu, Heng, Soutto, Mohammed, Capobianco, Anthony, Rai, Priyamvada, Zaika, Alexander, El-Rifai, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328352/
https://www.ncbi.nlm.nih.gov/pubmed/29991802
http://dx.doi.org/10.1038/s41388-018-0388-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328352/
https://www.ncbi.nlm.nih.gov/pubmed/29991802
http://dx.doi.org/10.1038/s41388-018-0388-8

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