A Fluorescent Glucose Transport Assay for Screening SGLT2 Inhibitors in Endogenous SGLT2-Expressing HK-2 Cells

ABSTRACT: The sodium-dependent glucose transporters 2 (SGLT2) plays important role in renal reabsorption of urinal glucose back to plasma for maintaining glucose homeostasis. The approval of SGLT2 inhibitors for treatment of type 2 diabetes highlights the SGLT2 as a feasible and promising drug targe...

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Detalles Bibliográficos
Autores principales: Lu, Yan-Ting, Ma, Xiu-Li, Xu, Yu-Hui, Hu, Jing, Wang, Fang, Qin, Wan-Ying, Xiong, Wen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328422/
https://www.ncbi.nlm.nih.gov/pubmed/30387082
http://dx.doi.org/10.1007/s13659-018-0188-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328422/
https://www.ncbi.nlm.nih.gov/pubmed/30387082
http://dx.doi.org/10.1007/s13659-018-0188-4

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