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A Fluorescent Glucose Transport Assay for Screening SGLT2 Inhibitors in Endogenous SGLT2-Expressing HK-2 Cells
ABSTRACT: The sodium-dependent glucose transporters 2 (SGLT2) plays important role in renal reabsorption of urinal glucose back to plasma for maintaining glucose homeostasis. The approval of SGLT2 inhibitors for treatment of type 2 diabetes highlights the SGLT2 as a feasible and promising drug targe...
Autores principales: | Lu, Yan-Ting, Ma, Xiu-Li, Xu, Yu-Hui, Hu, Jing, Wang, Fang, Qin, Wan-Ying, Xiong, Wen-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328422/ https://www.ncbi.nlm.nih.gov/pubmed/30387082 http://dx.doi.org/10.1007/s13659-018-0188-4 |
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