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HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway

Stem cell transplantation is a promising therapy for traumatic brain injury (TBI), but low efficiency of survival and differentiation of transplanted stem cells limits its clinical application. Histone deacetylase 1 (HDAC1) plays important roles in self-renewal of stem cells as well as the recovery...

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Detalles Bibliográficos
Autores principales: Xu, Ling, Xing, Qu, Huang, Tuanjie, Zhou, Jiankang, Liu, Tengfei, Cui, Yuanbo, Cheng, Tian, Wang, Yaping, Zhou, Xinkui, Yang, Bo, Yang, Greta Luyuan, Zhang, Jiewen, Zang, Xingxing, Ma, Shanshan, Guan, Fangxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328439/
https://www.ncbi.nlm.nih.gov/pubmed/30662396
http://dx.doi.org/10.3389/fncel.2018.00498