The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins

The mevalonate pathway provides sterols for membrane structure and nonsterol intermediates for the post-translational modification and membrane anchorage of growth-related proteins, including the Ras, Rac, and Rho GTPase family. Mevalonate-derived products are also essential for the Hedgehog pathway...

Descripción completa

Detalles Bibliográficos
Autores principales: Mo, Huanbiao, Jeter, Rayna, Bachmann, Andrea, Yount, Sophie T., Shen, Chwan-Li, Yeganehjoo, Hoda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328495/
https://www.ncbi.nlm.nih.gov/pubmed/30662405
http://dx.doi.org/10.3389/fphar.2018.01515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328495/
https://www.ncbi.nlm.nih.gov/pubmed/30662405
http://dx.doi.org/10.3389/fphar.2018.01515

Ejemplares similares