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Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer

Approximately 70% of patients with advanced breast cancer develop bone metastases, accompanied by complications, such as bone pain, fracture, and hypercalcemia. However, our understanding of the molecular mechanisms that govern this process remains fragmentary. Osterix (Osx) is a zinc finger-contain...

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Detalles Bibliográficos
Autores principales: Yao, Bing, Wang, Jue, Qu, Shuang, Liu, Yang, Jin, Yuci, Lu, Jianlei, Bao, Qianyi, Li, Lingyun, Yuan, Hongyan, Ma, Changyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328543/
https://www.ncbi.nlm.nih.gov/pubmed/30631043
http://dx.doi.org/10.1038/s41419-018-1269-3