Differential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4(+)Foxp3(+) induced Treg cells in vitro and in vivo periphery in autoimmune diseases

Tumor Necrosis Factor (TNF) α is a multifunctional cytokine with pro-inflammatory and anti-inflammatory characteristics. Increasing evidence suggests that thymus-derived, natural regulatory T cells (nTreg) express a remarkably high level of TNF Receptor 2 (TNFR2) and TNFα modulates the number or fun...

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Detalles Bibliográficos
Autores principales: Yang, Sujuan, Xie, Chichu, Chen, Ye, Wang, Julie, Chen, Xiaoqing, Lu, Zhengqi, June, Rayford R., Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328545/
https://www.ncbi.nlm.nih.gov/pubmed/30631042
http://dx.doi.org/10.1038/s41419-018-1266-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328545/
https://www.ncbi.nlm.nih.gov/pubmed/30631042
http://dx.doi.org/10.1038/s41419-018-1266-6

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