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Paternal Age and Transgenerational Telomere Length Maintenance: A Simulation Model

Telomere length (TL) in offspring is positively correlated with paternal age at the time of the offspring conception. The paternal-age-at-conception (PAC) effect on TL is puzzling, and its biological implication at the population level is unknown. Using a probabilistic model of transgenerational TL...

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Detalles Bibliográficos
Autores principales: Horvath, K., Eisenberg, D., Stone, R., Anderson, J., Kark, J., Aviv, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328556/
https://www.ncbi.nlm.nih.gov/pubmed/30631124
http://dx.doi.org/10.1038/s41598-018-36923-x