Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation

Induction of differentiation is a therapeutic strategy in high-risk neuroblastoma, a childhood cancer of the sympathetic nervous system. Neuroblastoma differentiation requires transcriptional upregulation of neuronal genes. How this process is regulated at epigenetic levels is not well understood. H...

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Detalles Bibliográficos
Autores principales: Yang, Liqun, Zha, Yunhong, Ding, Jane, Ye, Bingwei, Liu, Mengling, Yan, Chunhong, Dong, Zheng, Cui, Hongjuan, Ding, Han-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328563/
https://www.ncbi.nlm.nih.gov/pubmed/30631055
http://dx.doi.org/10.1038/s41389-018-0112-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328563/
https://www.ncbi.nlm.nih.gov/pubmed/30631055
http://dx.doi.org/10.1038/s41389-018-0112-0

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