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Shifts in the selectivity filter dynamics cause modal gating in K(+) channels
Spontaneous activity shifts at constant experimental conditions represent a widespread regulatory mechanism in ion channels. The molecular origins of these modal gating shifts are poorly understood. In the K(+) channel KcsA, a multitude of fast activity shifts that emulate the native modal gating be...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328603/ https://www.ncbi.nlm.nih.gov/pubmed/30631074 http://dx.doi.org/10.1038/s41467-018-07973-6 |