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VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection

Helicobacter pylori (H. pylori) is the causative agent of gastric cancer, making it the only bacterium to be recognized as a Class I carcinogen by the World Health Organization. The virulence factor cytotoxin associated gene A (CagA) is a known oncoprotein that contributes to the development of gast...

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Detalles Bibliográficos
Autores principales: Abdullah, Majd, Greenfield, Laura K., Bronte-Tinkew, Dana, Capurro, Mariana I., Rizzuti, David, Jones, Nicola L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328614/
https://www.ncbi.nlm.nih.gov/pubmed/30631092
http://dx.doi.org/10.1038/s41598-018-37095-4