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CD44v6 engages in colorectal cancer progression

CD44 is a transmembrane glycoprotein. When the CD44 gene is expressed, its pre-messenger RNA (mRNA) can be alternatively spliced into mature mRNAs that encode several CD44 isoforms. The mRNA assembles with ten standard exons, and the sixth variant exon encodes CD44v6, which engages in a variety of b...

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Detalles Bibliográficos
Autores principales: Ma, Lixin, Dong, Lihua, Chang, Pengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328617/
https://www.ncbi.nlm.nih.gov/pubmed/30631039
http://dx.doi.org/10.1038/s41419-018-1265-7