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Critical Appraisal of Programmed Death Ligand 1 Reflex Diagnostic Testing: Current Standards and Future Opportunities

INTRODUCTION: Patient suitability to anti–programmed death ligand 1 (PD-L1) immune checkpoint inhibition is key to the treatment of NSCLC. We present, applied to PD-L1 testing: a comprehensive cross-validation of two immunohistochemistry (IHC) clones; our descriptive experience in diagnostic reflex...

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Detalles Bibliográficos
Autores principales: Humphries, Matthew P., McQuaid, Stephen, Craig, Stephanie G., Bingham, Victoria, Maxwell, Perry, Maurya, Manisha, McLean, Fiona, Sampson, James, Higgins, Patricia, Greene, Christine, James, Jacqueline, Salto-Tellez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328626/
https://www.ncbi.nlm.nih.gov/pubmed/30296485
http://dx.doi.org/10.1016/j.jtho.2018.09.025