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Identification and characterization of GLDC as host susceptibility gene to severe influenza

Glycine decarboxylase (GLDC) was prioritized as a candidate susceptibility gene to severe influenza in humans. The higher expression of GLDC derived from genetic variations may confer a higher risk to H7N9 and severe H1N1 infection. We sought to characterize GLDC as functional susceptibility gene th...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Wang, Dong, Wong, Bosco Ho‐Yin, Li, Cun, Poon, Vincent Kwok‐Man, Wen, Lei, Zhao, Xiaoyu, Chiu, Man Chun, Liu, Xiaojuan, Ye, Ziwei, Yuan, Shuofeng, Sze, Kong‐Hung, Chan, Jasper Fuk‐Woo, Chu, Hin, To, Kelvin Kai‐Wang, Yuen, Kwok Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328914/
https://www.ncbi.nlm.nih.gov/pubmed/30498026
http://dx.doi.org/10.15252/emmm.201809528