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Blocking of checkpoint receptor PD-L1 aggravates osteoarthritis in macrophage-dependent manner in the mice model

As a chronic degenerative joint disease, osteoarthritis is among the most common diseases all over the world. In osteoarthritis, inflammation plays an important role in the generation of joint symptoms and the development of disease. When the programmed cell death-1 (PD-1)/programmed death-ligand 1...

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Detalles Bibliográficos
Autores principales: Liu, Shenghou, Mi, Jiqiang, Liu, Wenguang, Xiao, Shipeng, Gao, Chunzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328950/
https://www.ncbi.nlm.nih.gov/pubmed/30791745
http://dx.doi.org/10.1177/2058738418820760