Cargando…

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

BACKGROUND: Uncontrolled microglial activation contributes to the pathogenesis of various neurodegenerative diseases. Previous studies have shown that proinflammatory microglia are powered by glycolysis, which relays on high levels of glucose uptake. This study aimed to understand how glucose uptake...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Luxi, Pavlou, Sofia, Du, Xuan, Bhuckory, Mohajeet, Xu, Heping, Chen, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329071/
https://www.ncbi.nlm.nih.gov/pubmed/30634998
http://dx.doi.org/10.1186/s13024-019-0305-9