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Glucose transporter 1 critically controls microglial activation through facilitating glycolysis
BACKGROUND: Uncontrolled microglial activation contributes to the pathogenesis of various neurodegenerative diseases. Previous studies have shown that proinflammatory microglia are powered by glycolysis, which relays on high levels of glucose uptake. This study aimed to understand how glucose uptake...
Autores principales: | Wang, Luxi, Pavlou, Sofia, Du, Xuan, Bhuckory, Mohajeet, Xu, Heping, Chen, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329071/ https://www.ncbi.nlm.nih.gov/pubmed/30634998 http://dx.doi.org/10.1186/s13024-019-0305-9 |
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