Chemo-immunotherapy improves long-term survival in a preclinical model of MMR-D-related cancer

BACKGROUND: Mismatch Repair Deficiency (MMR-D)-related tumors are highly immunogenic and constitute ideal vaccination targets. In a proof-of-concept study delayed tumorigenesis and prolonged survival has been shown in a clinically-relevant mouse model for MMR-D-related diseases (=MLH1 knock out mice...

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Detalles Bibliográficos
Autores principales: Maletzki, Claudia, Wiegele, Leonie, Nassar, Ingy, Stenzel, Jan, Junghanss, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329128/
https://www.ncbi.nlm.nih.gov/pubmed/30630527
http://dx.doi.org/10.1186/s40425-018-0476-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329128/
https://www.ncbi.nlm.nih.gov/pubmed/30630527
http://dx.doi.org/10.1186/s40425-018-0476-x

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