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Correlate tumor mutation burden with immune signatures in human cancers

BACKGROUND: Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response and cancer prognosis. Although many explorations have revealed that high TMB may yield many neoantigens to incite antitumor immune response, a systematic exploration of the correlation between TMB and...

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Detalles Bibliográficos
Autores principales: Wang, Xiaosheng, Li, Mengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329192/
https://www.ncbi.nlm.nih.gov/pubmed/30634925
http://dx.doi.org/10.1186/s12865-018-0285-5