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Correlate tumor mutation burden with immune signatures in human cancers
BACKGROUND: Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response and cancer prognosis. Although many explorations have revealed that high TMB may yield many neoantigens to incite antitumor immune response, a systematic exploration of the correlation between TMB and...
Autores principales: | Wang, Xiaosheng, Li, Mengyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329192/ https://www.ncbi.nlm.nih.gov/pubmed/30634925 http://dx.doi.org/10.1186/s12865-018-0285-5 |
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