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Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract

Background: Cervical-vaginal fluid (CVF) hydrates the mucosa of the lower female reproductive tract and is known to contain numerous proteases. The low pH of CVF (4.5 or below in healthy women of reproductive age) is a uniquely human attribute and poses a challenge for the proteolytic functioning of...

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Detalles Bibliográficos
Autores principales: Muytjens, Carla M.J., Yu, Yijing, Diamandis, Eleftherios P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329257/
https://www.ncbi.nlm.nih.gov/pubmed/30647911
http://dx.doi.org/10.12688/f1000research.16255.2