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Human ESC-Derived Cardiomyocytes Restore Function in Infarcted Hearts of Non-Human Primates

Pluripotent stem cell–derived cardiomyocyte grafts can remuscularize substantial amounts of infarcted myocardium and beat in synchrony with the heart, but in some settings cause ventricular arrhythmias. It is unknown whether human cardiomyocytes can restore cardiac function in a physiologically rele...

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Detalles Bibliográficos
Autores principales: Liu, Yen-Wen, Chen, Billy, Yang, Xiulan, Fugate, James A., Kalucki, Faith A., Futakuchi-Tsuchida, Akiko, Couture, Larry, Vogel, Keith W., Astley, Clifford A., Baldessari, Audrey, Ogle, Jason, Don, Creighton W., Steinberg, Zachary L., Seslar, Stephen P., Tuck, Stephanie A., Tsuchida, Hiroshi, Naumova, Anna V., Dupras, Sarah K., Lyu, Milly S., Lee, James, Hailey, Dale W., Reinecke, Hans, Pabon, Lil, Fryer, Benjamin H., MacLellan, W. Robb, Thies, R. Scott, Murry, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329375/
https://www.ncbi.nlm.nih.gov/pubmed/29969440
http://dx.doi.org/10.1038/nbt.4162