Impaired autophagic and mitochondrial functions are partially restored by ERT in Gaucher and Fabry diseases

The major cellular clearance pathway for organelle and unwanted proteins is the autophagy-lysosome pathway (ALP). Lysosomes not only house proteolytic enzymes, but also traffic organelles, sense nutrients, and repair mitochondria. Mitophagy is initiated by damaged mitochondria, which is ultimately d...

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Detalles Bibliográficos
Autores principales: Ivanova, Margarita M., Changsila, Erk, Iaonou, Chidima, Goker-Alpan, Ozlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329517/
https://www.ncbi.nlm.nih.gov/pubmed/30633777
http://dx.doi.org/10.1371/journal.pone.0210617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329517/
https://www.ncbi.nlm.nih.gov/pubmed/30633777
http://dx.doi.org/10.1371/journal.pone.0210617

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