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Chemogenomic model identifies synergistic drug combinations robust to the pathogen microenvironment
Antibiotics need to be effective in diverse environments in vivo. However, the pathogen microenvironment can have a significant impact on antibiotic potency. Further, antibiotics are increasingly used in combinations to combat resistance, yet, the effect of microenvironments on drug-combination effi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329523/ https://www.ncbi.nlm.nih.gov/pubmed/30596642 http://dx.doi.org/10.1371/journal.pcbi.1006677 |