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Genetic regulation of the placental transcriptome underlies birth weight and risk of childhood obesity

GWAS identified variants associated with birth weight (BW), childhood obesity (CO) and childhood BMI (CBMI), and placenta is a critical organ for fetal development and postnatal health. We examined the role of placental transcriptome and eQTLs in mediating the genetic causes for BW, CO and CBMI, and...

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Detalles Bibliográficos
Autores principales: Peng, Shouneng, Deyssenroth, Maya A., Di Narzo, Antonio F., Cheng, Haoxiang, Zhang, Zhongyang, Lambertini, Luca, Ruusalepp, Arno, Kovacic, Jason C., Bjorkegren, Johan L. M., Marsit, Carmen J., Chen, Jia, Hao, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329610/
https://www.ncbi.nlm.nih.gov/pubmed/30596636
http://dx.doi.org/10.1371/journal.pgen.1007799