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A PDE1 inhibitor reduces adipogenesis in mice via regulation of lipolysis and adipogenic cell signaling

Vinpocetine, a phosphodiesterase (PDE) type-1 inhibitor, increases cAMP and cGMP levels and is currently used for the management of cerebrovascular disorders, such as stroke, cerebral hemorrhage, and cognitive dysfunctions. In this study, we first determined that vinpocetine effectively suppressed a...

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Detalles Bibliográficos
Autores principales: Kim, Nam-Jun, Baek, Jung-Hwan, Lee, JinAh, Kim, HyeNa, Song, Jun-Kyu, Chun, Kyung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329698/
https://www.ncbi.nlm.nih.gov/pubmed/30635550
http://dx.doi.org/10.1038/s12276-018-0198-7