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Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis

In humans and in mice the formation of nephrons during embryonic development reaches completion near the end of gestation, after which no new nephrons are formed. The final nephron complement can vary 10-fold, with reduced nephron number predisposing individuals to hypertension, renal, and cardiovas...

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Detalles Bibliográficos
Autores principales: Yermalovich, Alena V., Osborne, Jihan K., Sousa, Patricia, Han, Areum, Kinney, Melissa A., Chen, Michael J., Robinton, Daisy A., Montie, Helen, Pearson, Dan S., Wilson, Sean B., Combes, Alexander N., Little, Melissa H., Daley, George Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329821/
https://www.ncbi.nlm.nih.gov/pubmed/30635573
http://dx.doi.org/10.1038/s41467-018-08127-4