Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

TRAF-binding domain (Trabid), one of deubiquitination enzymes, was recently reported to activate Wnt/ β-catenin signaling pathway. However, the role of Trabid in tumors including hepatocellular carcinoma (HCC) and the underlying mechanisms controlling its activity remain poorly understood. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yuekun, Qu, Chao, Hong, Xuehui, Jia, Yanyan, Lin, Meihua, Luo, Yunmei, Lin, Fengqin, Xie, Xiaolong, Xie, Xiaoqi, Huang, Juan, Wu, Qin, Qiu, Xingfeng, Piao, Daxun, Xing, Yanwei, Yu, Tian, Lu, Yuanfu, Huang, Qiang, Yu, Changyin, Jin, Junfei, Zhang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329825/
https://www.ncbi.nlm.nih.gov/pubmed/29748601
http://dx.doi.org/10.1038/s41418-018-0119-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329825/
https://www.ncbi.nlm.nih.gov/pubmed/29748601
http://dx.doi.org/10.1038/s41418-018-0119-2

Ejemplares similares