MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration

Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra (SN) and the reduction of dopamine levels in the striatum. Although details of the molecular mechanisms underlying dopaminergic neuronal death in PD rema...

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Detalles Bibliográficos
Autores principales: Lee, Eunju, Hwang, Inhwa, Park, Sangjun, Hong, Sujeong, Hwang, Boreum, Cho, Yoeseph, Son, Junghyun, Yu, Je-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329843/
https://www.ncbi.nlm.nih.gov/pubmed/29786072
http://dx.doi.org/10.1038/s41418-018-0124-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329843/
https://www.ncbi.nlm.nih.gov/pubmed/29786072
http://dx.doi.org/10.1038/s41418-018-0124-5

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