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Oral co-administration of a bacterial protease inhibitor in the vaccine formulation increases antigen delivery at the intestinal epithelial barrier

The study of capture and processing of antigens (Ags) by intestinal epithelial cells is very important for development of new oral administration systems. Efficient oral Ag delivery systems must resist enzymatic degradation by gastric and intestinal proteases and deliver the Ag across biological bar...

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Detalles Bibliográficos
Autores principales: Coria, Lorena M., Risso, Gabriela S., Guaimas, Francisco F., Ferrero, Mariana C., Bruno, Laura, Pasquevich, Karina A., Cassataro, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329890/
https://www.ncbi.nlm.nih.gov/pubmed/30496771
http://dx.doi.org/10.1016/j.jconrel.2018.11.025