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Stem cell models of human synapse development and degeneration

Many brain disorders exhibit altered synapse formation in development or synapse loss with age. To understand the complexities of human synapse development and degeneration, scientists now engineer neurons and brain organoids from human-induced pluripotent stem cells (hIPSC). These hIPSC-derived bra...

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Detalles Bibliográficos
Autores principales: Wilson, Emily S., Newell-Litwa, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329912/
https://www.ncbi.nlm.nih.gov/pubmed/30475098
http://dx.doi.org/10.1091/mbc.E18-04-0222