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Stem cell models of human synapse development and degeneration
Many brain disorders exhibit altered synapse formation in development or synapse loss with age. To understand the complexities of human synapse development and degeneration, scientists now engineer neurons and brain organoids from human-induced pluripotent stem cells (hIPSC). These hIPSC-derived bra...
Autores principales: | Wilson, Emily S., Newell-Litwa, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329912/ https://www.ncbi.nlm.nih.gov/pubmed/30475098 http://dx.doi.org/10.1091/mbc.E18-04-0222 |
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