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Identification and Functional Characterization of a New Splicing Variant of EZH2 in the Central Nervous System

EZH2 plays vital roles in epigenetic regulation, neuronal development and cancer progression. Here a novel EZH2 variant, namely EZH2-X9 (X9 for short) resulting from alternative splicing, was isolated, identified and functionally characterized. X9 was highly expressed in the brains of SD rats, indic...

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Detalles Bibliográficos
Autores principales: Li, Danyang, Wang, Hui-Li, Huang, Xiyao, Gu, Xiaozhen, Xue, Weizhen, Xu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329929/
https://www.ncbi.nlm.nih.gov/pubmed/30662348
http://dx.doi.org/10.7150/ijbs.28129