Cargando…
TranscriptClean: variant-aware correction of indels, mismatches and splice junctions in long-read transcripts
MOTIVATION: Long-read, single-molecule sequencing platforms hold great potential for isoform discovery and characterization of multi-exon transcripts. However, their high error rates are an obstacle to distinguishing novel transcript isoforms from sequencing artifacts. Therefore, we developed the pa...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329999/ https://www.ncbi.nlm.nih.gov/pubmed/29912287 http://dx.doi.org/10.1093/bioinformatics/bty483 |