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TranscriptClean: variant-aware correction of indels, mismatches and splice junctions in long-read transcripts
MOTIVATION: Long-read, single-molecule sequencing platforms hold great potential for isoform discovery and characterization of multi-exon transcripts. However, their high error rates are an obstacle to distinguishing novel transcript isoforms from sequencing artifacts. Therefore, we developed the pa...
Autores principales: | Wyman, Dana, Mortazavi, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329999/ https://www.ncbi.nlm.nih.gov/pubmed/29912287 http://dx.doi.org/10.1093/bioinformatics/bty483 |
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