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Accurate multiple alignment of distantly related genome sequences using filtered spaced word matches as anchor points

MOTIVATION: Most methods for pairwise and multiple genome alignment use fast local homology search tools to identify anchor points, i.e. high-scoring local alignments of the input sequences. Sequence segments between those anchor points are then aligned with slower, more sensitive methods. Finding s...

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Detalles Bibliográficos
Autores principales: Leimeister, Chris-André, Dencker, Thomas, Morgenstern, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330006/
https://www.ncbi.nlm.nih.gov/pubmed/29992260
http://dx.doi.org/10.1093/bioinformatics/bty592