Uncertainty quantification, propagation and characterization by Bayesian analysis combined with global sensitivity analysis applied to dynamical intracellular pathway models

MOTIVATION: Dynamical models describing intracellular phenomena are increasing in size and complexity as more information is obtained from experiments. These models are often over-parameterized with respect to the quantitative data used for parameter estimation, resulting in uncertainty in the indiv...

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Detalles Bibliográficos
Autores principales: Eriksson, Olivia, Jauhiainen, Alexandra, Maad Sasane, Sara, Kramer, Andrei, Nair, Anu G, Sartorius, Carolina, Hellgren Kotaleski, Jeanette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330009/
https://www.ncbi.nlm.nih.gov/pubmed/30010712
http://dx.doi.org/10.1093/bioinformatics/bty607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330009/
https://www.ncbi.nlm.nih.gov/pubmed/30010712
http://dx.doi.org/10.1093/bioinformatics/bty607

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