ncdDetect2: improved models of the site-specific mutation rate in cancer and driver detection with robust significance evaluation

MOTIVATION: Understanding the mutational processes that act during cancer development is a key topic of cancer biology. Nevertheless, much remains to be learned, as a complex interplay of processes with dependencies on a range of genomic features creates highly heterogeneous cancer genomes. Accurate...

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Detalles Bibliográficos
Autores principales: Juul, Malene, Madsen, Tobias, Guo, Qianyun, Bertl, Johanna, Hobolth, Asger, Kellis, Manolis, Pedersen, Jakob Skou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330011/
https://www.ncbi.nlm.nih.gov/pubmed/29945188
http://dx.doi.org/10.1093/bioinformatics/bty511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330011/
https://www.ncbi.nlm.nih.gov/pubmed/29945188
http://dx.doi.org/10.1093/bioinformatics/bty511

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