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ncdDetect2: improved models of the site-specific mutation rate in cancer and driver detection with robust significance evaluation
MOTIVATION: Understanding the mutational processes that act during cancer development is a key topic of cancer biology. Nevertheless, much remains to be learned, as a complex interplay of processes with dependencies on a range of genomic features creates highly heterogeneous cancer genomes. Accurate...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330011/ https://www.ncbi.nlm.nih.gov/pubmed/29945188 http://dx.doi.org/10.1093/bioinformatics/bty511 |